Clindamycin + Clotrimazole Vaginal Gel 2% w/w

What is Clindamycin and Clotrimazole Vaginal Gel 2%?

Clindamycin and Clotrimazole Vaginal Gel 2% is a prescription treatment used when a woman is facing both a bacterial and a fungal vaginal infection at the same time. This kind of mixed infection is more common than people realize, and it’s often missed or misdiagnosed. You start with itching, maybe a strange discharge, maybe odor, and it keeps coming back even after using regular yeast or bacterial meds. That’s where this gel helps.

It combines two trusted ingredients: clindamycin, which targets bacteria, and clotrimazole, which works on yeast. Together, they clear both infections without needing separate products or multiple steps. This gel is inserted directly into the vagina where the infection lives, and it begins working locally—giving targeted relief.

Sanford Pharmacy offers the genuine version, not a lookalike or swap. They ship discreetly, securely, and with care, so you get what your doctor intended—no confusion, no old stock.

Drug Class

Clindamycin and clotrimazole don’t come from the same family. That’s why they work so well together. Clindamycin belongs to a class called lincosamide antibiotics. It’s usually used in infections where oxygen isn’t needed by the bacteria—that’s why it’s perfect for the vaginal environment, which is low in oxygen.

Clotrimazole is from the imidazole antifungal group. It’s used for yeast infections of the mouth, skin, and vagina. Most people have heard of clotrimazole cream, often used on the skin or around the vaginal opening.

When doctors prescribe both, it means there’s more going on than just yeast. This gel simplifies that plan by giving both ingredients at once—clindamycin clotrimazole, together, where it’s needed.

What Are The Benefits Of Clindamycin and Clotrimazole Vaginal Gel?

🢂  Treats both bacterial and yeast infections in one gel
🢂  Reduces itching, odor, discharge, and irritation
🢂  Ideal when regular yeast meds haven’t fully worked
🢂  No need for two products or separate doses
🢂  Acts locally with limited systemic absorption
🢂  Often used in stubborn or chronic vaginal issues
🢂  Helpful after antibiotic treatment that triggered yeast growth
🢂  Simplifies recovery and supports full tissue healing
🢂  Frequently recommended in tough-to-diagnose vaginal discomfort
🢂  Available at Sanford Pharmacy—real stock, no generic swap unless you ask

Sometimes, symptoms stick around because one medication only handles half the problem. This cream is meant to deal with both.

How Does Clindamycin and Clotrimazole Work

Clindamycin stops bacterial growth

It works by binding to the part of the bacteria that makes proteins. Without those proteins, the bacteria can’t multiply. It slowly reduces the population until your body can finish the job.

Clotrimazole damages fungal cells

Yeast cells have a wall that holds their shape and protects them. Clotrimazole cream interferes with a key part of that wall, making it leak and fall apart. That stops the yeast from spreading or surviving.

Working together

This gel combines both actions, so you don’t have to wonder if the issue is bacterial or fungal. Whether it started as one or turned into both, clindamycin and clotrimazole cream brings you a better shot at complete relief.

This isn’t the same clindamycin topical that’s used on the face for acne, or clindamycin for UTI. It’s formulated for the vaginal tissue—so don’t use it elsewhere.

Onset of Action

You might notice relief within 24 to 48 hours. The burning might ease first. Itching, odor, and discharge follow. But don’t stop using it early. Even if you feel better quickly, finishing the full course helps prevent it from coming back.

The yeast symptoms might take a little longer to fade. That’s normal. Yeast cells don’t die off all at once. They shrink slowly, especially if they’ve been there for a while.

It’s not unusual to feel extra moisture during treatment—that’s part of the gel and the body flushing things out.

How to Use Clindamycin and Clotrimazole Vaginal Gel

Apply before bed

The gel is best used at night, so it can stay in place. Lie back, insert the applicator gently, and dispense the full dose. Try not to get up right away.

Use the applicator correctly

One applicator per dose. Wash your hands before and after. You don’t need to clean deep inside—just rinse the applicator with warm soapy water if it’s reusable.

Finish the course

Most treatments last 3 or 7 nights, depending on the strength and what your doctor prescribed. Don’t stop if your symptoms improve on day 2. Stopping early can leave some bacteria or yeast behind.

Avoid sex during treatment, and don’t use tampons. The gel can weaken condoms or diaphragms, so use caution if you’re relying on those methods.

Available Forms

⮞  Clindamycin and Clotrimazole Vaginal Gel 2%
⮞  Clindamycin gel and clindamycin cream for skin or acne
⮞  Clotrimazole cream for yeast infection sold over the counter
⮞  Clotrimazole cream vaginal products in non-prescription strength
⮞  Single tubes or multi-dose packs available
⮞  Sanford Pharmacy carries all approved forms—always sealed and shipped fresh

How This Product Differs From Others

Most people use clotrimazole cream when they think they have a yeast infection. And it works—for yeast. But if there’s bacteria too, it can leave the infection half-treated.

Some antibiotics help with bacteria but let yeast grow. That’s why many end up using clindamycin for acne or another antibiotic, only to develop a yeast infection after. This gel addresses both problems at once.

Instead of comparing clotrimazole vs clindamycin, this product combines both in the right doses. One tube, one applicator, one schedule. Simple, reliable, and faster recovery.

Dosage Information

Missed dose instructions

If you miss a dose, don’t panic. Apply the next one as soon as you remember. If it’s close to your next dose time, skip the missed one—don’t use double.

Overuse or accidental extra dose

Using too much can cause irritation, extra discharge, or mild cramps. It won’t heal you faster. Just go back to your regular schedule and let your provider know if anything feels off.

Storage Information

⪢  Store at room temperature. Avoid heat or freezing.

⪢  Don’t keep it in your bathroom cabinet if it gets steamy.

⪢  Keep it sealed, clean, and out of reach of children.

⪢  Check the expiration date before each course.

⪢  If the tube looks discolored or smells strange, don’t use it.

⪢  Sanford Pharmacy always ships fresh stock—you won’t get anything close to expiry.

Warnings and Precautions

🚨 If you’re pregnant or breastfeeding, ask before using. Many providers still prescribe it, but only when needed. Always discuss risks and benefits first.

🚨 Don’t use this cream during your period—it can reduce effectiveness. Wait until bleeding stops to begin or continue your course.

🚨 If you’ve had allergic reactions to clindamycin, clotrimazole, or other vaginal creams, let your provider know. Rashes, irritation, or swelling might be signs of allergy.

🚨 This product is for vaginal use only. Don’t apply it to broken skin, don’t eat it, and don’t use it elsewhere on your body.

Drug-to-Drug Interactions

Clindamycin and clotrimazole may react with:

➣  Warfarin
➣  Antifungal pills
➣  Oral antibiotics
➣  Certain antidepressants
➣  Hormone therapy
➣  Supplements with zinc or calcium (interfere with absorption)

Even if it’s used locally, some ingredients get absorbed into your body. Tell your doctor everything you’re taking—even if it seems unrelated.

Drug-to-Food Interactions

➣  Food won’t directly interfere with clindamycin and clotrimazole cream, but your diet can influence vaginal health.

➣  Sugary or yeast-heavy diets may worsen fungal overgrowth.

➣  Staying hydrated, eating fiber, and limiting sugar may help treatment.

➣  Avoid alcohol during treatment if possible. It’s not directly harmful here, but it can worsen side effects like nausea or bloating.

Side Effects

➽  Mild vaginal burning
➽  Itching after application
➽  Extra discharge
➽  Spotting or light bleeding
➽  Mild abdominal cramps
➽  Temporary bloating
➽  Tiredness
➽  Backache
➽  Loss of appetite (rare)
➽  Slight headache

These are usually temporary. If any become severe or don’t go away after treatment, stop and consult your doctor.

Conclusion

Clindamycin and Clotrimazole Vaginal Gel 2% is one of the most useful treatments for women dealing with mixed vaginal infections. When one ingredient isn’t enough, this combination gives your body the push it needs to finally clear the infection and restore balance.

It’s gentle where it needs to be and powerful where it counts. Used as directed, it brings relief and helps avoid future flare-ups. If you’ve been cycling through creams and pills with no clear answer, this may be the one that works.

Order from Sanford Pharmacy for discreet, safe, and accurate delivery. What you’re prescribed is what you get—no guesswork, no delays.

FAQs

Can I use this gel while on my period?

Does it treat yeast or bacteria?

Can I use clotrimazole cream at the same time?

Is this the same as clindamycin for UTI?

When will symptoms start to go away?