Tenvir-EM (Emtricitabine 200mg + Tenofovir 300mg) 300mg + 200mg

Emtricitabine 200mg + Tenofovir 300mg

What is Emtricitabine 200mg + Tenofovir 300mg?

Emtricitabine 200mg + Tenofovir 300mg is prescribed with other HIV medicines to effectively control HIV infection. It is a combination of two drugs, including Emtricitabine and Tenofovir. Tenvir EM is a combination of emtricitabine and tenofovir used for HIV treatment and PrEP.

Tenofovir is a nucleotide reverse transcriptase inhibitor, whereas emtricitabine is a nucleoside. This combination of medicines helps to reduce the amount of HIV in your body so that the immune system can work properly. Tenvir contains tenofovir disoproxil fumarate and is used to treat HIV and chronic hepatitis B.

In this way, your risk of getting HIV complications like new infections is lowered, and your quality of life is improved. To control your HIV infection, do not use this medication by itself. Doing so might make your treatment less effective.

A combination treatment of emtricitabine 200 mg and tenofovir 300 mg, along with one other HIV medicine, must be used. This medication is also helpful in preventing HIV infection in people suffering from a high risk of infection.

Some things that increase risk include being involved in unprotected sexual activity, having a partner who is infected with HIV, infection with a sexually transmitted disease, or use of alcohol. Tenvir-EM helps prevent HIV when taken consistently as part of a PrEP regimen.

You need to know that Emtricitabine and tenofovir are not a cure for HIV infection. To reduce your risk of spreading HIV disease to another person, continue taking all HIV medicines as directed by your doctor.

Make sure to use an effective barrier method when indulging in sexual activity, as advised by your doctor. You can save on emtricitabine/tenofovir price by ordering it from a licensed online pharmacy. Tenvir AF 25 mg contains tenofovir alafenamide, a newer formulation with reduced kidney toxicity.

How does Emtricitabine 200mg + Tenofovir 300mg work?

You need to know that Emtricitabine and Tenofovir are a combination of two anti-HIV medications. Many people prefer to buy Tenvir-EM online for convenience and affordability.

They work by preventing HIV from multiplying in your body and reducing the amount of virus. Emtricitabine and tenofovir disoproxil fumarate tablets 200mg/300mg are used in PrEP and HIV treatment.

This medicine also increases the CD4 cell count in your blood. CD4 is a white blood cells that protect against infection.

How to use Emtricitabine 200mg + Tenofovir 300mg ?

Before starting treatment with Emtricitabine 200mg + Tenofovir 300mg, carefully read the patient information leaflet provided with the medicine itself. Ask your doctor about this drug and its dosage if you have any questions.

Take this medication by mouth with a glass of plain water; do not break, chew, or crush it. Make sure you take this medication at the same time every day so that you do.

Dosage of Emtricitabine + Tenofovir Disoproxil is based on your medical condition, kidney function, and body’s response to treatment. Emtricitabine and tenofovir disoproxil fumarate tablets 200mg/300mg PrEP are widely prescribed to reduce the risk of HIV infection.

Doctors recommend this medicine to children based on their weight. When using it to treat HIV infection, take Emtricitabine + Tenofovir with other medicines that treat HIV effectively.

In case you take didanosine enteric-coated tablets, then take both medicines either on an empty stomach or with a light meal. When you take didanosine buffered tablets, then take both medicines on an empty stomach or as directed by a doctor.

It is necessary to continue taking this medicine exactly in the same way as your doctor has prescribed. For the best effect, you must take this medication at evenly spaced times. Emtricitabine and tenofovir disoproxil fumarate tablets 200mg 300mg PrEP help prevent HIV when taken daily.

Do not take more or less of this drug than directed, or stop taking it even for a short time unless suggested by your doctor. Doing so might cause the amount of virus to increase in your body and make infection more difficult to treat or worsen side effects.

Indications/Usage

Tenvir-EM consists of emtricitabine 200 mg and tenofovir disoproxil fumarate 300 mg, which is equivalent to tenofovir disoproxil 245 mg. These two substances are antiviral drugs belonging to the group of nucleoside or nucleotide reverse transcriptase inhibitors.

This drug combination is used together with other antiretroviral drugs for treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults and children who satisfy applicable weight requirements. Tenvir-EM is not a complete therapy of HIV infection and should be used as a component of a regimen prescribed by a physician.

Additionally, emtricitabine and tenofovir disoproxil fumarate may be prescribed for HIV pre-exposure prophylaxis (PrEP), also referred to as prophylaxis, for HIV negative adults and adolescents with body weight equal or above 35 kg who have risk of HIV-1 infection acquisition via sexual contact. In turn, PrEP should be used together with safe sex practices, regular testing for HIV and proper medical follow-up. In addition, HIV negative status should be confirmed before using PrEP and at least once every three months while treatment.

The medicine works by inhibiting HIV reverse transcriptase, an enzyme which is necessary for reproduction of genetic material of the virus. This leads to lowering the quantity of HIV in the organism during the treatment or preventing the establishment of HIV infection when the drug is taken properly as PrEP.

Tenvir-EM cannot cure HIV infection and cannot guarantee protection against its acquisition. Patients with hepatitis B should be tested regularly and monitored due to the fact that both active components influence hepatitis B virus. Severe deterioration of the condition can happen after stopping the treatment.

Contact your physician if your symptoms persist or if the medicine does not show sufficient results.

Missed dose

🔹 In case you miss a dose of Emtricitabine + Tenofovir tablet, then take it as soon as you remember.

🔹 But if it’s time for your next dose, then skip your missed one and continue the next scheduled dosage at the regular time.

🔹 Just to catch up on missed doses, you must never double the dosage because this will cause severe side effects.

Overdose

If you have overdosed and suffer from serious symptoms like passing out or trouble breathing, then contact a doctor immediately.

Usual Dosage

Depends on the disease, age, weight, functioning of organs, individual response to the treatment.

Recommended prescription information usually states:

For HIV-1 infection treatment in adults and pediatric patients weighting at least 35 kg, the usual dose is one tablet with emtricitabine 200 mg and tenofovir disoproxil fumarate 300 mg once daily, with or without food. It should be used in combination with other appropriate HIV medicines.

For HIV PrEP in HIV negative adults and adolescents with body weight at least 35 kg, the usual dose is one tablet once daily with or without food. Daily dose of one tablet is maximum routine dosage for patients with adequate kidney function.

For HIV infection treatment in adults with creatinine clearance of 30-49 ml/min, the recommended dosage is one tablet every 48 hours. It is not recommended for HIV treatment when the creatinine clearance is below 30 ml/min or when the patient requires hemodialysis.

In case of PrEP, the combination is not recommended if the creatinine clearance is below 60 ml/min. Kidney function should be assessed before the treatment and monitored during the treatment period. The dosage should not be altered or suspended without medical advice.

Dosage and schedule of use are decided by your physician.

Strength

200 mg emtricitabine + 300 mg tenofovir disoproxil fumarate per film-coated tablet

Precautions and warnings

Before you take Emtricitabine/Tenofovir, inform your doctor if you are allergic to either of the medicines or have any other allergies. Some of the inactive chemicals in this medication may cause allergic reactions or other issues.

It is necessary to inform the doctor about your medical history, especially of:

Emtricitabine/Tenofovir can make you feel dizzy. Avoid alcohol consumption as it can make you suffer from dizziness. If it is not safe to do so, avoid using heavy machinery, driving, and other tasks requiring attentiveness.

This medication should only be used as directed during pregnancy. Make sure to discuss all benefits and risks with your doctor. Emtricitabine 200mg/tenofovir 300mg is a key combination used in HIV prevention and treatment.


In case you have an HIV infection, then treatment might lower your risk of passing HIV infection to your baby and this medicine will be part of treatment.

This medicine passes into breast milk but is unlikely to harm your nursing infant. If you suffer from HIV, then breast milk might transmit HIV.

Side effects of Emtricitabine 200mg + Tenofovir 300mg

Common and Mild Side Effects

• Diarrhea
• Nausea
• Headache
• Tiredness or fatigue
• Dizziness
• Problems with sleep
• Bizarre dreams
• Drug rash
• Abdominal pain
• Low appetite

Usually, these side effects are mild and temporary. Contact your physician if a side effect becomes unpleasant or persistent.

Storage

🔹 It is suggested to store Emtricitabine 200mg + Tenofovir 300mg at room temperature right away from moisture and light.

🔹 Keep this medicine away from children and pets. Properly discard this drug when it expires or is no longer required.

Interactions

🔹 Drug interactions might change how your medicines work or increase the risk of suffering from severe side effects.

🔹 Never begin, cease, or adjust the dosage of any drug without a doctor's approval.

🔹 Keep a list of all products you use, including herbal supplements and prescription & non-prescription medicines, and share it with your doctor.

🔹 Do not take this medicine with other products that contain Emtricitabine/Tenofovir.

🔹 Some other medicines treat HIV infection that can interact with Tenofovir.

To avoid drug interactions, you must avoid taking the following medicines with Emtricitabine/Tenofovir:

Drug Interactions

Medicines that may Interact

The use of other medicines which contain emtricitabine, tenofovir disoproxil fumarate or tenofovir alafenamide is not recommended because this may result in repetition of antiviral treatment. Also, the combination should not be used with adefovir dipivoxil.

Both active substances are primarily excreted from the body by kidneys. Medicines which decrease the ability of kidneys or compete for their excretion may increase the concentrations of tenofovir and emtricitabine, increasing the risk of renal side effects. For example, acyclovir, valacyclovir, cidofovir, ganciclovir, valganciclovir, aminoglycosides, e.g., gentamicin, and high doses or multiple courses of nonsteroidal anti-inflammatory medicines, e.g., ibuprofen, naproxen.

Tenofovir may increase the concentration of didanosine, which increases the risk of didanosine related adverse effects. When tenofovir is co-administered with atazanavir, atazanavir levels may decrease if the regimen is not adequately managed with ritonavir. Also, lopinavir with ritonavir, ritonavir-boosted darunavir, and some other combinations of antiretroviral agents may increase tenofovir exposure.

Some medicines for treating hepatitis C, such as ledipasvir with sofosbuvir, sofosbuvir with velpatasvir, and sofosbuvir with velpatasvir and voxilaprevir, may increase tenofovir exposure. The risk of increasing tenofovir exposure may be higher when these medicines are used with HIV regimens that include ritonavir or cobicistat and kidney monitoring may be required. 

Potential Interaction Effects

Interactions may increase the risk of renal toxicity, increase the incidence of side effects caused by medicines, change the levels of antiviral medicines or reduce the effectiveness of the treatment. Your physician may order tests for kidneys, change the regimen of treatment or prescribe another medicine if there is a clinically significant interaction.

Tell your physician and pharmacist about all medicines, dietary supplements and herbs that you are currently using before starting the treatment.

 Frequently asked questions about Emtricitabine 200mg + Tenofovir 300mg (FAQs)

 Is Emtricitabine 200mg + Tenofovir 300mg safe?

🔹 Yes, this medicine is safe to take when used in dosage and duration as directed by your doctor.

🔹 Take it exactly in the same way as directed by a doctor and do not skip any doses.

🔹 If any side effects of this medicine bother you, then immediately contact your doctor.

Does Emtricitabine 200mg + Tenofovir 300mg provide effective results?

🔹 When used in the dose and duration as recommended by a doctor, this medication is effective.

🔹 Do not stop taking it even if you experience improvements within a few days. If you stop, this medicine will cause the symptoms will return or worsen. 

What if you miss a dose of Emtricitabine 200mg + Tenofovir 300mg?

If you have missed a dose of this medicine, then take it as soon as possible. Do not double the dosage to make up for a missed dose, as this can increase the risk of developing side effects.

Medically reviewed by the Sanford Pharmacy Pharmacists Medical Team

Medical References:

• FDA Prescribing Information – Truvada (Emtricitabine and Tenofovir Disoproxil Fumarate Tablets)
  https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/021752s064lbl.pdf
• DailyMed – Truvada (Emtricitabine and Tenofovir Disoproxil Fumarate)
  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=54e82b13-a037-49ed-b4b3-030b37c0ecdd
• DailyMed – Emtricitabine and Tenofovir Disoproxil Fumarate Tablets
  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e1e4d828-7870-4ea9-a66a-e658487bd859
• MedlinePlus – Emtricitabine and Tenofovir Disoproxil Fumarate
  https://medlineplus.gov/druginfo/meds/a612036.html
• EMA – Truvada Product Information
  https://www.ema.europa.eu/en/documents/product-information/truvada-epar-product-information_en.pdf
  
  
  Note: Content Information on Sanford Pharmacy is meant for general information and should not be seen as medical advice. Please consult a licensed healthcare provider before using any medicine. Self-treatment without guidance is not recommended.