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Zestoretic categories/t2q9KBns5bUDcJBezCR1WqY3S.png categories/hxWDeAiHxsPpsVRtDf2wP5iSD.jpg


Manufacturer : Generic | Active substance : Lisinopril and Hydrochlorothiazide | Prescription : Not Required

Zestoretic contains a combination of hydrochloroyhiazide and Lisinopril. Hydrochlorothiazide is a thiazide diuretic that restricts your body from absorbing too much salt, causing fluid retention.

Zestoretic 5/12.5mg

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Method of Usage



What is Zestoretic?


Zestoretic contains a combination of hydrochloroyhiazide and Lisinopril.


Hydrochlorothiazide is a thiazide diuretic that restricts your body from absorbing too much salt, causing fluid retention. 


Lisinopril is an ACE inhibitor that helps in lowering blood pressure and relieves the symptoms of fluid retention.


The doctor might recommend Zestoretic 5/12.5mg when one drug is not effective in controlling your blood pressure.


You might also be directed to take the individual drug first and then begin this combination medication.


Remember controlling your high blood pressure can help in lowering the risk of heart attack or stroke.


It is important for you to start this medicine for treating hypertension only after the prescription of the doctor.


However, before you decide to order Zestoretic, it is necessary to consult the doctor once.


You can easily buy Zestoretic5/12.5 mg tablets from a licensed online pharmacy at a pocket-friendly price.



How does Zestoretic work?


This medication works by relaxing your blood vessels in order to ensure blood flows smoothly.


It also helps you to make more urine so that extra salt and water are eliminated from the body.


After two weeks of taking Zestoretic medicine, you can find improvement in your blood pressure.

How to use Zestoretic?

Read the patient information leaflet carefully before starting your treatment with this medication.


If you have any doubts or questions in your mind then discuss them with the doctor once.


Take Zestoretic tablet by mouth with or without the food as recommended by your doctor.


Remember this medicine is taken only once a day mainly in the morning.


In case, this medicine causes you to urinate frequently then take it almost 4 hours before bedtime.


This will help you to prevent getting up again and again to urinate.


When taking other drugs to lower cholesterol then take Zestoretic almost 4 hours before or 4 hours after taking those medicines.


Depending upon your medical condition and response to treatment, the doctor will recommend a dosage of Zestoretic.


If you suffer from ongoing vomiting or diarrhea or sweating more than usual then call the doctor immediately.


When using this medication, you might easily become dehydrated.


This further can lead to the problems of low blood pressure, kidney failure, or electrolyte disorders.


To get the most benefit from it, you must use Zestoretic on a regular basis.


Take this medicine at the same time every day so that you remember taking it.


Even if you start feeling well after a few days, you must continue taking this medicine for the full prescribed time.


Many people suffering from high blood pressure do not feel sick.


When using this medicine, your blood pressure must be checked often and the doctor might also suggest blood tests occasionally.


In case, you undergo any kind of surgery then inform the doctor beforehand about using the Zestoretic pill.    


Keep one thing in your mind, high blood pressure has no symptoms.


As a result, you might require to use Zestoretic for the rest of your life to treat blood pressure.   


If you find that your experience does not improve or gets worse then inform the doctor well in advance.


In case, you overdose and experience serious symptoms like passing out or trouble to breathe then tell the doctor.


If you miss a dose then immediately take the missed dose.


However, if it’s time for the next prescribed dosage then continue with the regular dose and skip the missed dosage.

Initially, 10/12.5 mg of zestoretic is usually taken daily.

A healthcare provider may change the prescribed dosage of Zestoretic.

A person's answer will determine the maximum daily dosage of 40/25 mg.

For ideal blood pressure management, zestoretic should be used as directed.

Zestoretic dosage modifications, where necessary, are ensured by routine monitoring.

Just to make up for the missed dose, you must never take two doses at the same time.

This can lead to overdose and cause severe side effects like headache, nausea, and dizziness.


Zestoretic precautions and warnings


You must not use this medicine, if you are allergic to Lisinopril or Hydrochlorothiazide or if:


  • You are not able to urinate
  • You suffer from an allergic reaction to any ACE inhibitor including captopril, ramipril, quinap, benazepril, etc.
  • You have hereditary angioedema
  • You experience an allergy to sulfa medications
  • You took a heart medication known as sacubitril recently

Even if you suffer from any allergies like rashes, flushing, etc. then inform the doctor about it beforehand.


Before starting the use of the Zestoretic pill, tell the doctor about your medical history including:

  •  lood filtering processes like LDL apheresis, dialysis
  • Skin cancer
  • Kidney disorder
  • History of allergic reactions like swelling of your lips/face/throat/tongue
  • Liver disease
  • Gout
  • Lupus

Also, inform the doctor well in advance about using other products like herbal supplements, prescription, and non-prescription pills.


All this information will help your doctor to prescribe the dosage of Zestoretic accordingly and adjust the dosage of other medicines.


In case, you have diabetes then this drug might affect your blood sugar.


Get your blood sugar checked regularly and share the results with your doctor.


Depending upon the report, the doctor might make changes in your diabetes medicine, diet, or exercise program.


Zestoretic side effects


While your body adjusts to this medicine, you might experience dizziness, tiredness, headache, or light-headedness.


Getting up slowly from a sitting or lying position can help you to decrease the risk of dizziness.


A number of people using this medication do not suffer from any serious side effects.


Some of the common side effects of the Zestoretic tablet include:



Decrease in vision and eye pain

Symptoms of the high potassium blood level

Signs of kidney problems

Irregular heartbeat



Get emergency medical help, if any of these side effects continue or become worse.







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